A private jet crashed into houses in Philadelphia on Friday night, just two days after a plane-helicopter collision occurred near Washington, D.C. 

Transportation Secretary Sean Duffy said that six people were reportedly aboard the plane that crashed into the homes, which caused an explosion and set multiple homes on fire. The crash occurred around 6:30 p.m.

The jet was equipped with medical equipment. Two of the passengers were reportedly doctors and one was a pediatric patient, along with family members. 

Injuries have also been reported on the ground, but it is not clear how many people have been injured. The status of the six individuals on the plane was not immediately known. 

The Federal Aviation Administration said in a statement on X that the jet departed from Northeast Philadelphia Airport and was en route to Springfield-Branson National Airport in Missouri. 

"The FAA and [National Transportation Safety Board (NTSB)] will investigate," the FAA said. "The NTSB will lead the investigation and will provide all updates."

A video of the crash can be viewed here.

Police told CBS News that some cars in the area were hit by the plane and some businesses near the Roosevelt Mall are also on fire. 

The cause of the crash was not immediately clear.

This story is developing and will be updated as more information comes in.

Misty Severi is a news reporter for Just The News. You can follow her on X for more coverage.